Article

LFMM 2.0: Latent factor models for confounder adjustment in genome and epigenome-wide association studies

2018-01-30

Abstract excerpt

<h4>Motivation</h4> Genome-wide, epigenome-wide and gene-environment association studies are plagued with the problems of confounding and causality. Although those problems have received considerable attention in each application field, no consensus have emerged on which approaches are the most appropriate to solve this problem. Current methods use approximate heuristics for estimating confounders, and often igno...

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Literature Corpus work: f72bacbb-3050-5d28-8539-2cda90dfc04e
DOI: 10.1101/255893

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