Article

S100A8/A9 predicts triple-negative breast cancer response to PIM kinase and PD-1/PD-L1 inhibition

2023-09-23

Abstract excerpt

<h4>ABSTRACT</h4> It remains elusive why some triple-negative breast cancer (TNBC) patients respond poorly to existing therapies while others respond well. Our retrospective analysis of historical gene expression datasets reveals that increased expression of immunosuppressive cytokine S100A8/A9 in early-stage tumors is robustly associated with subsequent disease progression in TNBC. Although it has recently gaine...

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Literature Corpus work: f6f7a2e6-3153-56c8-996d-e1f99414a6c4
DOI: 10.1101/2023.09.21.558870

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