Article

Piezo1 is required for outflow tract and aortic valve development

2019-01-23

Abstract excerpt

<h4>Aims-</h4> During embryogenesis, the onset of circulatory blood flow generates a variety of hemodynamic forces which reciprocally induce changes in cardiovascular development and performance. It has been known for some time that these forces can be detected by as yet unknown mechanosensory systems which in turn promote cardiogenic events such as outflow tract and aortic valve development. PIEZO1 is a mechanos...

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Literature Corpus work: f6e7b2de-e885-5442-8b16-a08696d17203
DOI: 10.1101/528588

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