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Mechanosensing by Piezo1 and its implications for physiology and various pathologies

15 Nov 2021

Abstract excerpt

Piezo1 is a mechanosensitive ion channel with essential roles in cardiovascular, lung, urinary, and immune functions. Piezo1 is widely distributed in different tissues in the human body and its specific roles have been identified following a decade of research; however, not all are well understood. Many structural and functional characteristics of Piezo1 have been discovered and are known to differ greatly from...

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PMID: 34781417
DOI: 10.1111/brv.12814

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