Back to search

Article

<i>Plasmodium falciparum</i> contains functional SCF and CRL4 ubiquitin E3 ligases, and CRL4 is critical for cell division and membrane integrity

2023-04-18

Abstract excerpt

Protein ubiquitination is essential for cellular homeostasis and regulation of several processes, including cell division and genome integrity. Ubiquitin E3 ligases determine substrate specificity for ubiquitination, and Cullin-RING ubiquitin E3 Ligases (CRLs) make the largest group among the ubiquitin E3 ligases. Although conserved and most studied in model eukaryotes, CRLs remain underappreciated in Plasmodium...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f6c825b4-bf33-5bd7-a62d-52c59a5949b8
DOI
10.1101/2023.04.18.537323
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
<i>Plasmodium falciparum</i> contains functional SCF and CRL4 ubiquitin E3 ligases, and CRL4 is critical for cell division and membrane integrityDOI 10.1101/2023.04.18.537323
The Skp1-Cullin1-FBXO1 complex is a pleiotropic regulator required for the formation of gametes and motile forms in Plasmodium bergheiSemantic proximity
Understanding the role of RBR-E3 ligase in regulation of cellular homeostasis in human malaria parasiteSemantic proximity
Proximity interaction analysis of the <i>Plasmodium falciparum</i> putative ubiquitin ligase <i>Pf</i> RNF1 reveals a role in RNA regulationSemantic proximity
The Plasmodium falciparum RING Finger Protein PfRNF1 Forms an Interaction Network with Regulators of Sexual DevelopmentSemantic proximity
Protein ubiquitylation is essential for the schizont to merozoite transition in <i>Plasmodium falciparum</i> blood-stage developmentSemantic proximity
CRL Ubiquitin Ligases and DNA Damage ResponseSemantic proximity
Drug resistance-associated mutations in <i>Plasmodium</i> UBP-1 disrupt ubiquitin hydrolysisSemantic proximity
Cellular and molecular basis of <i>Pf</i> Coronin function in artemisinin resistance in <i>Plasmodium falciparum</i>Semantic proximity
Targeting the Plasmodium Ubiquitin/Proteasome System with Anti- Malarial Compounds: Promises for the FutureSemantic proximity
Interferon-Inducible E3 Ligase RNF213 Facilitates Host-Protective Linear and K63-Linked Ubiquitylation of Toxoplasma gondii Parasitophorous VacuolesSemantic proximity
<i>Toxoplasma gondii</i> F-Box Protein L2 Silences Feline-Restricted Genes Necessary for Sexual CommitmentSemantic proximity
CRL4s: the CUL4-RING E3 ubiquitin ligases.Semantic proximity
Select a neighboring publication to make it the new centre.