Article

Collaboration Between Host and Viral Factors Shape SARS-CoV-2 Evolution

2021-07-16

Abstract excerpt

SARS-CoV-2 continues to evolve, resulting in several ‘variants of concern’ with novel properties. The factors driving SARS-CoV-2 fitness and evolution in the human respiratory tract remain poorly defined. Here, we provide evidence that both viral and host factors co-operate to shape SARS-CoV-2 genotypic and phenotypic change. Through viral whole-genome sequencing, we explored the evolution of two clinical isolates...

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Literature Corpus work: f697d0e5-1047-5619-8f19-6a548a7e99da
DOI: 10.1101/2021.07.16.452629

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