Article
Comparison of SARS-CoV-2 Evolution in Paediatric Primary Airway Epithelial Cell Cultures Compared with Vero-Derived Cell Lines.
Viruses - 5 Feb 2022
Bamford Connor G G, Broadbent Lindsay, Aranday-Cortes Elihu, McCabe Mary, McKenna James, Courtney David G, Touzelet Olivier, Ali Ahlam, Roberts Grace, Lopez Campos Guillermo, Simpson David, McCaughey Conall, Fairley Derek, Mills Ken, Power Ultan F, On Behalf Of The Breathing Together Investigators
Abstract excerpt
SARS-CoV-2 can efficiently infect both children and adults, albeit with morbidity and mortality positively associated with increasing host age and presence of co-morbidities. SARS-CoV-2 continues to adapt to the human population, resulting in several variants of concern (VOC) with novel properties, such as Alpha and Delta. However, factors driving SARS-CoV-2 fitness and evolution in paediatric cohorts remain...
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