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Article

Analyzing the Androgen Receptor Interactome in Prostate Cancer: Implications for Therapeutic Intervention

9 Mar 2022

Abstract excerpt

The androgen receptor (AR) is a member of the ligand-activated nuclear receptor family of transcription factors. AR's transactivation activity is turned on by the binding of androgens, the male sex steroid hormones. AR is critical for the development and maintenance of the male phenotype but has been recognized to also play an important role in human diseases. Most notably, AR is a major driver of prostate cancer...

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PMID: 35326387
DOI: 10.3390/cells11060936

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