Article
Development and validation of a six-RNA binding proteins prognostic signature and candidate drugs for prostate cancer.
Genomics - 1 Nov 2020
Gao Lei, Meng Jialin, Zhang Yong, Gu Junfei, Han Zhenwei, Wang Xiaolu, Gao Shenglin
Abstract excerpt
The dysregulation of RNA binding proteins (RBPs) regulates the progression of several cancers. However, information on the overall functions of RBPs in prostate cancer (PCa) remains largely understudied. Therefore, based on the TCGA dataset, this study identified 144 differentially expressed RBPs in tumors compared to normal tissues. Subsequently, through univariate, LASSO and multivariate Cox regression...
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