Article

<i>Ex vivo</i> quantification of anti-tumor T-cell activity upon anti-PD-1 treatment in patient-derived lung tumor-on-chip

2023-06-22

Abstract excerpt

<h4>ABSTRACT</h4> There is a compelling need for new approaches to predict efficacy of immunotherapy drugs. Tumor-on-chip technology exploits microfluidics to generate 3D cell co-cultures embedded in hydrogels that recapitulate immune and stromal characteristics of a simplified tumor ecosystem. Here, we present the development and validation of lung-tumor-on-chip platforms to quickly and precisely measure ex viv...

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Literature Corpus work: f63b4f2c-afe9-5b00-b4c5-0c89f4e08e3e
DOI: 10.1101/2023.06.21.545960

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