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A patient-specific lung cancer assembloid model with heterogeneous tumor microenvironments

20 Apr 2024

Abstract excerpt

Cancer models play critical roles in basic cancer research and precision medicine. However, current in vitro cancer models are limited by their inability to mimic the three-dimensional architecture and heterogeneous tumor microenvironments (TME) of in vivo tumors. Here, we develop an innovative patient-specific lung cancer assembloid (LCA) model by using droplet microfluidic technology based on a microinjection...

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PMID: 38643164
DOI: 10.1038/s41467-024-47737-z

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