Article

Monoclonal Antibodies Against Mature Interleukin-18 Ameliorate Colitis and Repair Goblet Cell Function

2024-01-19

Abstract excerpt

<title>Abstract</title> <p>Numerous biological interventions and small molecules are used to treat Crohn’s disease; however, the effectiveness of these treatments varies largely. Non-responsiveness to biological therapies is associated with interleukin (IL)-18 gene polymorphisms and high IL-18 expression has been implicated in the pathogenesis of Crohn’s disease. This study aimed to elucidate the expressions of p...

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Literature Corpus work: f61e152f-2489-56d8-a683-368b6613de75
DOI: 10.21203/rs.3.rs-3859077/v1

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