Article

Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia

2019-03-11

Abstract excerpt

<h4>Summary</h4> Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons. While several inherited pathogenic mutations have been identified as causative, the vast majority of cases are sporadic with no family history of disease. Thus, for the majority of ALS cases, a specific causal abnormality is not known and the disease may be a product of...

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Literature Corpus work: f5c4e532-69ba-5f72-b694-cfb8fc2bdf3a
DOI: 10.1101/574509

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