Article

Comparative Evaluation of Adeno-Associated Virus and Lentivirus Mediated Gene Transfer in Adult Rat Optic Nerve

2026-05-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The optic nerve serves as a vital conduit for visual signaling, and its degeneration in optic neuropathy results in irreversible vision loss. It is also a widely used model for studying central nervous system (CNS) injury and repair. Although adeno-associated virus (AAV) and lentivirus are extensively applied in CNS research, their transduction efficiency and cell-type speci...

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Literature Corpus work: f5b5c5d5-65f3-5fed-8abc-1e0f6c24afb3
DOI: 10.64898/2026.05.12.724624

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