Article

SF3B4 Regulated Alternative Splicing that Produced an Oncogenic Isoform of HOXA11-AS to Promote Glycolytic Reprogramming and ESCC Progression

2023-07-11

Abstract excerpt

<title>Abstract</title> <p> Background Dysregulated splicing factors (SFs) and aberrant alternative splicing (AS) events are involved in tumor progression. However, the AS landscape underlying SFs dysregulation and the further signal transduction network were unraveled in esophageal squamous cell carcinoma (ESCC). This study revealed the biological function of splicing factor 3b subunit 4 (SF3B4) in non-coding...

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Literature Corpus work: f595a1c1-a089-5792-bf0e-52a7cb91aae7
DOI: 10.21203/rs.3.rs-3086784/v1

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