Back to search

Article

Robotic Handling Preserves Induced Pluripotent Stem Cell Derived Vascular Smooth Muscle Cells Differentiation using a Weekend-free, Automatable, Low-variability, Low-cost (WALL) Protocol

2025-11-28

Abstract excerpt

Vascular disease modeling and tissue engineering require scalable, efficient, and reproducible methods for differentiating cells, however no studies have validated whether automation, essential for scale-up, preserves differentiation quality in cells. Here, we developed a differentiation protocol for induced pluripotent stem cell (iPSC)-derived vascular smooth muscle cells (iVSMCs) that is applicable to both manua...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f5894816-a377-57a7-9ba6-d04e4a184583
DOI
10.1101/2025.11.25.690512
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Robotic Handling Preserves Induced Pluripotent Stem Cell Derived Vascular Smooth Muscle Cells Differentiation using a Weekend-free, Automatable, Low-variability, Low-cost (WALL) ProtocolDOI 10.1101/2025.11.25.690512
Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem CellsSemantic proximity
Phenotypes and Cellular Mechanics of Primary Human Aorta- and Pluripotent Stem Cell-derived Vascular Smooth Muscle CellsSemantic proximity
Growth Factor-Based Manufacturing of Human Pluripotent Stem Cell-Derived Cardiomyocytes Using the Vertical Wheel Bioreactor SystemSemantic proximity
Artery-on-chip demonstrates smooth muscle function comparable to both healthy and diseased living tissuesSemantic proximity
Engineered Microenvironment for Manufacturing Human Pluripotent Stem Cell-Derived Vascular Smooth Muscle CellsSemantic proximity
High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping.Semantic proximity
Vascular cells differentiated from peripheral blood mononuclear cell- versus urine cell-derived induced pluripotent stem cells: A comparative analysisSemantic proximity
Inducing highly physiologically relevant phenotypes of human vascular smooth muscle cells via 3D printingSemantic proximity
Efficient generation of hematopoietic progenitor cells from human pluripotent stem cells by robotic automationSemantic proximity
Genomic, transcriptomic and proteomic depiction of iPSC-derived smooth muscle cells as emerging cellular models for arterial diseasesSemantic proximity
Induced pluripotent stem cell-derived vascular smooth muscle cells: methods and applicationSemantic proximity
PLURIPOTENT STEM CELL-DERIVED CARDIOVASCULAR PROGENITORS DIFFFERENTIATED ON LAMININ 221 REGENERATE AND IMPROVE FUNCTION OF INFARCTED SWINE HEARTSSemantic proximity
Select a neighboring publication to make it the new centre.