Article

FIGL1 and its novel partner FLIP form a conserved complex that regulates homologous recombination

2017-07-06

Abstract excerpt

Homologous recombination is central to repair DNA double-strand breaks (DSB), either accidently arising in mitotic cells or in a programed manner at meiosis. Crossovers resulting from the repair of meiotic breaks are essential for proper chromosome segregation and increase genetic diversity of the progeny. However, mechanisms regulating CO formation remain elusive. Here, we identified through protein-protein inter...

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Literature Corpus work: f548ff3b-7871-5fc4-bf31-12da170ea313
DOI: 10.1101/159657

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