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Article

FIGL1 attenuates meiotic interhomolog repair and is counteracted by the RAD51 paralog XRCC2 and the chromosome axis protein ASY1 during meiosis.

The New phytologist - 1 Dec 2024

Emmenecker Côme, Pakzad Simine, Ture Fatou, Guerin Julie, Hurel Aurélie, Chambon Aurélie, Girard Chloé, Mercier Raphael, Kumar Rajeev

Abstract excerpt

Two recombinases, RAD51 and DMC1, catalyze meiotic break repair to ensure crossovers (COs) between homologous chromosomes (interhomolog) rather than between sisters (intersister). FIDGETIN-LIKE-1 (FIGL1) downregulates both recombinases. However, the understanding of how FIGL1 functions in meiotic repair remains limited. Here, we discover new genetic interactions of Arabidopsis thaliana FIGL1 that are important in...

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Share to Arabidopsis Proteins
Share to ATPases Associated with Diverse Cellular Activities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Cycle Proteins

Share to Chromosomes, Plant

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Share to Microtubule-Associated Proteins

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Source

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Identifiers

PMID: 39420761
DOI: 10.1111/nph.20181
PMCID: PMC11579446

Genes

RAD51
XRCC2
DMC1
RAD51B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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FIGL1 attenuates meiotic interhomolog repair and is counteracted by the RAD51 paralog XRCC2 and the chromosome axis protein ASY1 during meiosis.PMID 39420761Read ↗

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