Article

Dysregulation of Neuroprotective Lipoxin Pathway in Astrocytes in Response to Cytokines and Ocular Hypertension

2023-06-26

Abstract excerpt

Glaucoma leads to vision loss due to retinal ganglion cell death. Astrocyte reactivity contributes to neurodegeneration. Our recent study found that lipoxin B 4 (LXB 4 ), produced by retinal astrocytes, has direct neuroprotective actions on retinal ganglion cells. In this study, we aimed to investigate how the autacoid LXB 4 influences astrocyte activity in the retina under inflammatory cytokine-induced activat...

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Literature Corpus work: f5486ced-d2a4-53e6-becc-da8c5e0732a4
DOI: 10.1101/2023.06.22.546157

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