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Article

Lipocalin 2 Plays an Important Role in Regulating Inflammation in Retinal Degeneration

30 Mar 2018

Abstract excerpt

Abstract It has become increasingly important to understand how retinal inflammation is regulated because inflammation plays a role in retinal degenerative diseases. Lipocalin 2 (LCN2), an acute stress response protein with multiple innate immune functions, is increased in ATP-binding cassette subfamily A member 4 (Abca4)−/− retinol dehydrogenase 8 (Rdh8)−/− double-knockout mice, an animal model for Stargardt...

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PMID: 29602770
DOI: 10.4049/jimmunol.1701573

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