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Causal effects of circulating lipids and lipid-lowering drugs on the risk of atopic dermatitis: a mendelian randomization study.

Archives of dermatological research - 24 Dec 2024

Xu Guangquan, Chu Mengyang, Shen Shengxian, Miao Haijun, Bai Yaxing, Liu Xuan, Liu Wanting, Song Pu, Wang Lei, Fu Meng, Dang Erle, Shao Shuai, Wang Gang

Abstract excerpt

Lipid metabolism disorders are frequently noted in atopic dermatitis (AD) patients, prompting the long-term use of lipid-lowering drugs. However, the causal effects of circulating lipids and different lipid-lowering drugs on the risk of AD are not thoroughly understood. Using publicly available genome-wide association studies (GWAS) summary data from two different cohorts, a series of Mendelian randomization (MR)...

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Dermatitis, Atopic
Hypolipidemic Agents
Lipid Metabolism
Lipids
Lipoprotein Lipase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Membrane Transport Proteins

Mendelian Randomization Analysis

Proprotein Convertase 9

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PMID: 39718588
DOI: 10.1007/s00403-024-03635-4

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