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Renal mitochondrial injury in the pathogenesis of CKD: mtDNA and mitomiRs

1 Mar 2022

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Chronic kidney disease (CKD) is a public health concern that affects over 200 million people worldwide and is associated with a tremendous economic burden. Therefore, deciphering the mechanisms underpinning CKD is crucial to decelerate its progression towards end-stage renal disease (ESRD). Renal tubular cells are populated with a high number of mitochondria, which produce cellular energy and modulate several...

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Metabolism and Genetic Disorders
Mitochondrial Function and Pathology
Organ Transplantation Techniques and Outcomes

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PMID: 35260892
DOI: 10.1042/cs20210512

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