Article

ZMAT3 alleviates cell death of Fanconi Anemia deficient cells by modulating sphingolipid metabolism and ferroptosis.

2024-07-25

Abstract excerpt

<title>Abstract</title> <p>Fanconi Anemia (FA) is a genetic disorder marked by bone marrow failure and cancer risk. FA features continuous activation of the p53 pathway, leading to an exacerbated cellular response to stress and DNA damage and significantly altering cellular metabolism. Here, we pointed out for the first time the overexpression of ZMAT3, an RNA-binding protein, in murine FA-deficient hematopoietic...

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Literature Corpus work: f4e84445-3a39-55d6-9463-a2f06c524399
DOI: 10.21203/rs.3.rs-4668683/v1

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ZMAT3 alleviates cell death of Fanconi Anemia deficient cells by modulating sphingolipid metabolism and ferroptosis.DOI 10.21203/rs.3.rs-4668683/v1Read

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