3D-Printed Scaffolds Encapsulating Red Blood Cell Extracellular Vesicles for MicroRNA Delivery

Abstract excerpt

Small non-coding RNAs (sncRNA) hold promising therapeutic potential. However, their clinical application is hindered by the poor cytocompatibility and limited transfection efficiency of conventional delivery vectors. In contrast, red blood cell-derived extracellular vesicles (RBCEVs) offer a safer, more efficient, and cost-effective alternative. Given the limited studies on the application of RBCEVs in the central...

Topics

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• CRISPR and Genetic Engineering
• CRISPR-Cas Systems
• Extracellular Vesicles
• Gene Editing
• Gene Transfer Techniques
• Mutation
• Spine and Intervertebral Disc Pathology
• Tendon Structure and Treatment

Identifiers and source

Literature Corpus work

f4e43eef-caa0-5e96-841e-3483de5387ad

DOI

10.1101/2025.07.31.667777