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Attenuation of a DNA Cruciform by a Conserved Regulator Directs T3SS-1 mediated virulence in <i>Vibrio parahaemolyticus</i>

2022-03-07

Abstract excerpt

Pathogenic Vibrio species account for 3-5 million annual life-threatening human infections. Virulence is driven by bacterial hemolysin and toxin gene expression often positively regulated by the winged helix-turn-helix (wHTH) HlyU transcriptional regulator family and silenced by Histone-like nucleoid structural protein (H-NS). In the case of Vibrio parahaemolyticus , HlyU is required for virulence gene expressio...

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Literature Corpus work
f4d8f582-788c-5532-92e9-e89cf0d45224
DOI
10.1101/2022.03.07.483294
Open publication

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