Back to search

Article

Activation of the <i>Yersinia</i> type III secretion system induces large-scale chromosomal and virulence plasmid DNA rearrangements

2025-02-04

Abstract excerpt

The type III secretion system (T3SS) is used by Gram-negative bacteria, including important pathogens, to manipulate eukaryotic target cells by injecting effector proteins. Type III secretion and bacterial physiology are known to be tightly interconnected and influence each other. Most notably, secreting cells undergo growth arrest in the T3SS model organisms Yersinia , Salmonella and Shigella . The molecular b...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7dda044d-a997-5fa5-b131-813d65567ec2
DOI
10.1101/2025.02.04.636459
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Activation of the <i>Yersinia</i> type III secretion system induces large-scale chromosomal and virulence plasmid DNA rearrangementsDOI 10.1101/2025.02.04.636459
Molecular Pathogenesis of<i>Shigella</i>spp.: Controlling Host Cell Signaling, Invasion, and Death by Type III SecretionSemantic proximity
Dynamics of the Type III Secretion System Activity of Enteropathogenic Escherichia coliSemantic proximity
A chromosomally encoded type III secretion pathway in Yersinia enterocolitica is important in virulence.Semantic proximity
RNase-mediated reprogramming of <i>Yersinia</i> virulenceSemantic proximity
The <i>pcnB</i> gene sustains <i>Shigella flexneri</i> virulenceSemantic proximity
Translocation of surface-localized effectors in type III secretion.Semantic proximity
The polyadenylase PAPI is required for virulence plasmid maintenance in pathogenic bacteriaSemantic proximity
A translocation-competent pore is required for <i>Shigella flexneri</i> to escape from the double membrane vacuole during intercellular spreadSemantic proximity
Identification of chromosomal genes in Yersinia pestis that influence type III secretion and delivery of Yops into target cells.Semantic proximity
Regulation of the Yersinia type III secretion system: traffic control.Semantic proximity
Cytoplasmic targeting of IpaC to the bacterial pole directs polar type III secretion in Shigella.Semantic proximity
T6SS4 is heterogeneously expressed in <i>Y. pseudotuberculosis</i> and is a target for transcriptional and post-transcriptional regulationSemantic proximity
Select a neighboring publication to make it the new centre.