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Recombinant production in <i>Escherichia coli</i> of functionally active α-hemolysin from the human pathogen <i>Staphylococcus aureus</i>

2025-01-15

Abstract excerpt

Staphylococcus aureus is a human opportunistic pathogen capable of causing multiple infections in both humans and animals. It secretes a group of exotoxins, known as hemolysins, which are released to enhance its pathogenicity. All of them exhibit cytolytic activity on a variety of host cell types, but α-hemolysin stands out for being the most thoroughly studied variant. In this work, we show the production and pur...

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Literature Corpus work
f4c4bede-51b7-5383-bf97-c88ef0cd5839
DOI
10.1101/2025.01.14.632992
Open publication

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