Article
Ion channels and bacterial infection: the case of beta-barrel pore-forming protein toxins of Staphylococcus aureus.
FEBS letters - 18 Sept 2003
Menestrina G, Dalla Serra M, Comai M, Coraiola M, Viero G, Werner S, Colin D A, Monteil H, Prévost G
Abstract excerpt
Staphylococcus aureus strains causing human pathologies produce several toxins, including a pore-forming protein family formed by the single-component alpha-hemolysin and the bicomponent leukocidins and gamma-hemolysins. The last comprise two protein elements, S and F, that co-operatively form the active toxin. alpha-Hemolysin is always expressed by S. aureus strains, whereas bicomponent leukotoxins are more...
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