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Uncovering novel endolysins against methicillin-resistant <i>Staphylococcus aureus</i> using microbial single-cell genome sequencing

2023-06-22

Abstract excerpt

Endolysins, peptidoglycan hydrolases derived from bacteriophages (phages), are being developed as a promising alternative to conventional antibiotics. To obtain highly active endolysins, a diverse library of endolysins is vital. We here propose microbial single-cell genome sequencing as an efficient tool to discover dozens of previously unknown endolysins, owing to its culture-independent sequencing method. As a p...

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Identifiers and source

Literature Corpus work
1f35022e-149b-50f0-aae0-ee83395e93a3
DOI
10.1101/2023.06.22.546026
Open publication

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Uncovering novel endolysins against methicillin-resistant <i>Staphylococcus aureus</i> using microbial single-cell genome sequencingDOI 10.1101/2023.06.22.546026
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