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Chromatin profiling identifies transcriptional readthrough as a conserved mechanism for piRNA cluster biogenesis in mosquitoes

2022-08-22

Abstract excerpt

<h4>Summary</h4> The piRNA pathway in mosquitoes differs substantially from other model organisms, with an expanded PIWI gene family and functions in antiviral defense. Here, we defined core piRNA clusters as small RNA source loci that showed ubiquitous expression in both somatic and germline tissues. These core piRNA clusters were enriched for non-retroviral endogenous viral elements (nrEVEs) in antisense orient...

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Identifiers and source

Literature Corpus work
f227528b-dec5-5394-b659-e06f2783a97d
DOI
10.1101/2022.08.22.504762
Open publication

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Chromatin profiling identifies transcriptional readthrough as a conserved mechanism for piRNA cluster biogenesis in mosquitoesDOI 10.1101/2022.08.22.504762
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