Article
Adult Mouse Leptomeninges Exhibit Regional and Age-related Cellular Heterogeneity Implicating Mental Disorders
2023-09-13
Abstract excerpt
The leptomeninges envelop the central nervous system (CNS) and contribute to cerebrospinal fluid (CSF) production and homeostasis. We analyzed the meninges overlying the anterior or posterior forebrain in the adult mouse by single nuclear RNA-sequencing (snucRNA-seq). This revealed regional differences in fibroblast and endothelial cell composition and gene expression. Surprisingly, these non-neuronal cells co-exp...
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Identifiers and source
- Literature Corpus work
- 90e7cab1-0f97-5ed2-96a5-94b503c043a8
- DOI
- 10.1101/2023.09.10.557097