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The subcommissural organ regulates brain development via secreted peptides

2024-03-31

Abstract excerpt

The subcommissural organ (SCO) is a gland located at the entrance of the aqueduct of Sylvius in the brain. It exists in species as distantly related as amphioxus and humans, but its function is largely unknown. To explore its function, we compared transcriptomes of SCO and non-SCO brain regions and found three genes, Sspo , Car3 , and Spdef , that are highly expressed in the SCO. Mouse strains expressing Cre re...

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Identifiers and source

Literature Corpus work
baa37523-4f76-5624-bb2c-eaa351c91564
DOI
10.1101/2024.03.30.587415
Open publication

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The subcommissural organ regulates brain development via secreted peptidesDOI 10.1101/2024.03.30.587415
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