Back to search

Article

The Envelope Protein of Tick-Borne Encephalitis Virus Influence Neuron Entry, Pathogenicity and Vaccine Protection

2020-04-28

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Tick-borne encephalitis virus (TBEV) is considered to be the medically most important arthropod-borne virus in Europe. The symptoms of an infection ranges from subclinical to mild flu-like disease to lethal encephalitis. The exact determinants of disease severity are not known, however, the virulence of the strain as well as the immune status of the host are tho...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f47d3d62-df46-54ca-bcf2-141fbc66dbd8
DOI
10.21203/rs.3.rs-24796/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The Envelope Protein of Tick-Borne Encephalitis Virus Influence Neuron Entry, Pathogenicity and Vaccine ProtectionDOI 10.21203/rs.3.rs-24796/v1
The envelope protein of tick-borne encephalitis virus influences neuron entry, pathogenicity, and vaccine protectionSemantic proximity
The influence of the pre-membrane and envelope proteins on structure, pathogenicity and tropism of tick-borne encephalitis virusSemantic proximity
The neurovirulence and neuroinvasiveness of chimeric tick-borne encephalitis/dengue virus can be attenuated by introducing defined mutations into the envelope and NS5 protein genes and the 3' non-coding region of the genome.Semantic proximity
Viral Determinants of Virulence in Tick-Borne FlavivirusesSemantic proximity
The Relationship between the Structure of the Tick-Borne Encephalitis Virus Strains and Their Pathogenic PropertiesSemantic proximity
Characterization of monoclonal antibody-escape mutants of tick-borne encephalitis virus with reduced neuroinvasiveness in mice.Semantic proximity
Characterization and complete genome sequences of high- and low-virulence variants of tick-borne encephalitis virusSemantic proximity
The degree of attenuation of tick-borne encephalitis virus depends on the cumulative effects of point mutations.Semantic proximity
Venezuelan equine encephalitis virus variants lacking transcription inhibitory functions demonstrate highly attenuated phenotype.Semantic proximity
Amino acid changes responsible for attenuation of virus neurovirulence in an infectious cDNA clone of the Oshima strain of Tick-borne encephalitis virusSemantic proximity
Mice with different susceptibility to tick-borne encephalitis virus infection show selective neutralizing antibody response and inflammatory reaction in the central nervous system.Semantic proximity
The molecular biology of tick-borne encephalitis virusSemantic proximity
Select a neighboring publication to make it the new centre.