Article

Molecular and functional characterization of different BrainSphere models for use in neurotoxicity testing on microelectrode arrays

2023-03-13

Abstract excerpt

The currently accepted methods for neurotoxicity (NT) testing rely on animal studies. However, high costs and low testing throughput hinder their application for large numbers of chemicals. To overcome these limitations, in vitro methods are currently developed which are based on human induced pluripotent stem cells (hiPSC) that allow higher testing throughput at lower costs. We applied six different protocols to...

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Literature Corpus work: f43e02db-9f50-5451-8329-2cd0a015d77c
DOI: 10.1101/2023.03.13.532388

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