Article

Human-derived cortical neurospheroids coupled to passive, high-density and 3D MEAs: a valid platform for functional tests

2023-01-18

Abstract excerpt

With the advent of human-induced pluripotent stem cells (hiPSCs) differentiation protocols, different methods to create in-vitro human-derived neuronal networks have been proposed. Although monolayer cultures represent a valid model, adding three-dimensionality would make them more representative of an in-vivo environment. Thus, human-derived neurospheroids and brain-organoids are becoming increasingly used for...

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Literature Corpus work: c46d151a-8fcc-5282-8343-2c2f0ddbbee3
DOI: 10.1101/2023.01.17.524439

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