Article
Vhl deletion in <i>Dmp1</i> -expressing cells alters MEP metabolism and promotes stress erythropoiesis
2023-07-28
Abstract excerpt
<h4>ABSTRACT</h4> In recent years, general hypoxia-inducible factor (HIF)-prolyl hydroxylase (PHD) enzyme inhibitors have been developed for the treatment of anemia due to renal disease and osteoporosis. However, it remains a challenge to target the HIF signaling pathway without dysregulating the skeletal and hematopoietic system. Here, we examined the effects of Vhl deletion in bone by performing longitudinal a...
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Identifiers and source
- Literature Corpus work
- f3ff818c-0df8-5ae5-9b8b-4cf5a52377bb
- DOI
- 10.1101/2023.07.25.550559
