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Article

Vhl deletion in <i>Dmp1</i> -expressing cells alters MEP metabolism and promotes stress erythropoiesis

2023-07-28

Abstract excerpt

<h4>ABSTRACT</h4> In recent years, general hypoxia-inducible factor (HIF)-prolyl hydroxylase (PHD) enzyme inhibitors have been developed for the treatment of anemia due to renal disease and osteoporosis. However, it remains a challenge to target the HIF signaling pathway without dysregulating the skeletal and hematopoietic system. Here, we examined the effects of Vhl deletion in bone by performing longitudinal a...

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Literature Corpus work
f3ff818c-0df8-5ae5-9b8b-4cf5a52377bb
DOI
10.1101/2023.07.25.550559
Open publication

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Vhl deletion in <i>Dmp1</i> -expressing cells alters MEP metabolism and promotes stress erythropoiesisDOI 10.1101/2023.07.25.550559
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