Article

Single-cell RNA-Sequencing Co-Expression Analysis with CFTR in Lung Tissue

2024-05-17

Abstract excerpt

1 <h4>Background</h4> While cystic fibrosis is caused by loss-of-function variants in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) , other modifier genes have been shown to associate with disease severity. Co-expression of modifiers with CFTR in normal tissue indicates a cooperative relationship and suggests the potential for compensation in the presence of CFTR dysfunction. We examined the co-...

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Literature Corpus work: f3a94a4d-d7cb-52f1-8aab-ae9b33f9eeda
DOI: 10.1101/2024.05.14.594146

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