Article

From CFTR to a CF signalling network: a systems biology approach to study Cystic Fibrosis

2023-11-17

Abstract excerpt

<h4>Background</h4> Cystic Fibrosis (CF) is a monogenic disease caused by mutations in the gene coding the Cystic Fibrosis Transmembrane Regulator (CFTR) protein, but its overall physio-pathology cannot be solely explained by the loss of the CFTR chloride channel function. Indeed, CFTR belongs to a yet not fully deciphered network of proteins participating in various signalling pathways. <h4>Methods</h4> We prop...

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Literature Corpus work: bd6724aa-ee0b-5006-9604-635b5bf46aac
DOI: 10.1101/2023.11.15.567166

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