Article

CTRP7 as a Molecular Biomarker for Predicting Responsiveness to Pulmonary Vasodilators: Insights from Human and Animal Studies in Pulmonary Arterial Hypertension

2023-11-06

Abstract excerpt

<h4>Background</h4> Pulmonary arterial hypertension (PAH) is a life-threatening condition. Although pulmonary vasodilators have shown promise in managing PAH, the overall prognosis improvement is modest, partly because of the absence of a biomarker for guiding their selection. This study aimed to identify the molecular-based predictors of responsiveness to pulmonary vasodilators by combining human and basic studi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f3a0ae54-2221-59a7-a062-7e3ea239210f
DOI: 10.1101/2023.11.05.565725

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

CTRP7 as a Molecular Biomarker for Predicting Responsiveness to Pulmonary Vasodilators: Insights from Human and Animal Studies in Pulmonary Arterial HypertensionDOI 10.1101/2023.11.05.565725Read

Emerging Mechanistic Insights and Therapeutic Strategies for Pulmonary Arterial Hypertension: A Focus on Right Ventricular Dysfunction and Novel Treatment PathwaysSemantic proximity Read

Exploring hypoxia driven subtypes of pulmonary arterial hypertension through transcriptomics single cell sequencing and machine learningSemantic proximity Read

Single-cell characterization of the immune heterogeneity of pulmonary hypertension identifies novel targets for immunotherapySemantic proximity Read

Exploring the pathogenesis of pulmonary vascular diseaseSemantic proximity Read

Advances in diagnosis and patient profiling in pulmonary arterial hypertension for precision medicine.Semantic proximity Read

Individualized Interactomes from Pulmonary Arterial Hypertension Cell Biopsies Predict Therapeutic ResponseSemantic proximity Read

Recent advances in pulmonary arterial hypertensionSemantic proximity Read

Charting the cellular landscape of pulmonary arterial hypertension through single-cell omicsSemantic proximity Read

Peripheral Blood Signature of Vasodilator-Responsive Pulmonary Arterial HypertensionSemantic proximity Read

MicroRNAs in pulmonary arterial hypertension: pathogenesis, diagnosis and treatmentSemantic proximity Read

Novel Molecular Mechanisms of Pulmonary Hypertension: A Search for Biomarkers and Novel Drug Targets-From Bench to Bed Site.Semantic proximity Read

Using Omics to Understand and Treat Pulmonary Vascular DiseaseSemantic proximity Read