Article
Novel Molecular Mechanisms of Pulmonary Hypertension: A Search for Biomarkers and Novel Drug Targets-From Bench to Bed Site.
Oxidative medicine and cellular longevity - 1 Jan 2020
Gajecki Damian, Gawrys Jakub, Szahidewicz-Krupska Ewa, Doroszko Adrian
Abstract excerpt
Pulmonary hypertension (PH) is defined as increased mean pulmonary artery pressure (mPAP) above 25 mmHg, measured at rest by right heart catheterization. The exact global prevalence of PH is difficult to estimate, mainly due to the complex aetiology, and its spread may be underestimated. To date, numerous studies on the aetiology and pathophysiology of PH at molecular level were conducted. Simultaneously, some...
Topics
- Biomarkers
- Epigenesis, Genetic
- Humans
- Hypertension, Pulmonary
- Molecular Targeted Therapy
- Mutation
- Translational Research, Biomedical