Article

Recent advances in pulmonary arterial hypertension

2018-07-24

Abstract excerpt

Pulmonary arterial hypertension (PAH) is a rare disorder with a high mortality rate. Treatment options have improved in the last 20 years, but patients still die prematurely of right heart failure. Though rare, it is heterogeneous at the genetic and molecular level, and understanding and exploiting this is key to the development of more effective treatments. BMPR2 , encoding bone morphogenetic receptor type 2, is...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5eb058d7-184b-5c47-84bb-75a5dfd24064
DOI: 10.12688/f1000research.14984.1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Recent advances in pulmonary arterial hypertensionDOI 10.12688/f1000research.14984.1Read

Pulmonary arterial hypertension - progress in understanding the disease and prioritizing strategies for drug development.Semantic proximity Read

Emerging Mechanistic Insights and Therapeutic Strategies for Pulmonary Arterial Hypertension: A Focus on Right Ventricular Dysfunction and Novel Treatment PathwaysSemantic proximity Read

Understanding pulmonary hypertension: the need for an integrative metabolomics and transcriptomics approachSemantic proximity Read

Advances in diagnosis and patient profiling in pulmonary arterial hypertension for precision medicine.Semantic proximity Read

The Genetics of Pulmonary Arterial Hypertension in the <i>Post‐BMPR2</i> EraSemantic proximity Read

Using Omics to Understand and Treat Pulmonary Vascular DiseaseSemantic proximity Read

Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects.Semantic proximity Read

Narrative review: the enigma of pulmonary arterial hypertension: new insights from genetic studies.Semantic proximity Read

Novel Molecular Mechanisms of Pulmonary Hypertension: A Search for Biomarkers and Novel Drug Targets-From Bench to Bed Site.Semantic proximity Read

Developments in therapeutics for pulmonary arterial hypertension.Semantic proximity Read

BMPR2 Mutation and Metabolic Reprogramming in Pulmonary Arterial Hypertension.Semantic proximity Read

Identification of a novel mutation in the BMPR2 gene in a pulmonary arterial hypertension patient using next-generation sequencing.Semantic proximity Read