Article

Ancient DNA study provides clues to leprosy susceptibility in medieval Europe

2024-01-23

Abstract excerpt

<title>Abstract</title> <p>Background Leprosy is a chronic infectious disease caused by <italic>Mycobacterium leprae</italic> (<italic>M. leprae</italic>) that reached an epidemic scale in the Middle Ages. Nowadays, the disease is absent in Europe and host genetic influences have been considered as a contributing factor to leprosy disappearance. In this study, a case-control association analysis between multiple...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f380fc39-ccb3-5d31-ae29-164069af60ea
DOI: 10.21203/rs.3.rs-3879251/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Ancient DNA study provides clues to leprosy susceptibility in medieval EuropeDOI 10.21203/rs.3.rs-3879251/v1Read

Ancient DNA study provides clues to leprosy susceptibility in medieval Europe.Semantic proximity Read

Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans.Semantic proximity Read

Single nucleotide polymorphism analysis of European archaeological M. leprae DNA.Semantic proximity Read

Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomesSemantic proximity Read

Tuberculosis and leprosy associated with historical human population movements in Europe and beyond – an overview based on mycobacterial ancient DNASemantic proximity Read

A migration-driven model for the historical spread of leprosy in medieval Eastern and Central Europe.Semantic proximity Read

Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe.Semantic proximity Read

Molecular studies on ancient M. tuberculosis and M. leprae: methods of pathogen and host DNA analysis.Semantic proximity Read

Pre-European contact leprosy in the Americas and its current persistenceSemantic proximity Read

Ancient DNA Study in Medieval Europeans Shows an Association Between HLA-DRB1*03 and Paratyphoid Fever.Semantic proximity Read

On the origin of leprosy.Semantic proximity Read

Searching for signals of recent natural selection in genes of the innate immune response - ancient DNA study.Semantic proximity Read