Article
Single nucleotide polymorphism analysis of European archaeological M. leprae DNA.
PloS one - 22 Oct 2009
Watson Claire L, Lockwood Diana N J
Abstract excerpt
BACKGROUND: Leprosy was common in Europe eight to twelve centuries ago but molecular confirmation of this has been lacking. We have extracted M. leprae ancient DNA (aDNA) from medieval bones and single nucleotide polymorphism (SNP) typed the DNA, this provides insight into the pattern of leprosy transmission in Europe and may assist in the understanding of M. leprae evolution. METHODS AND FINDINGS: Skeletons have...
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