Article

SAKit: an all-in-one analysis pipeline for identifying novel protein caused by variant events at genomic and transcriptic level

2023-03-07

Abstract excerpt

<h4>Summary</h4> Genetic modifications that cause pivotal protein inactivation or abnormal activation may lead to cell signaling pathway change or even dysfunction, resulting in cancer and other diseases. In turn, dysfunction will further produce “novel proteins” that do not exist in the canonical human proteome. Identification of novel proteins is meaningful for identifying promising drug targets and developing...

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Literature Corpus work: 8db1d4af-94ee-5b1e-b0f0-5103c0760fbf
DOI: 10.1101/2023.03.06.531407

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