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Article

Non-synonymous variations in cancer and their effects on the human proteome: workflow for NGS data biocuration and proteome-wide analysis of TCGA data.

BMC bioinformatics - 27 Jan 2014

Cole Charles, Krampis Konstantinos, Karagiannis Konstantinos, Almeida Jonas S, Faison William J, Motwani Mona, Wan Quan, Golikov Anton, Pan Yang, Simonyan Vahan, Mazumder Raja

Abstract excerpt

BACKGROUND: Next-generation sequencing (NGS) technologies have resulted in petabytes of scattered data, decentralized in archives, databases and sometimes in isolated hard-disks which are inaccessible for browsing and analysis. It is expected that curated secondary databases will help organize some of this Big Data thereby allowing users better navigate, search and compute on it. RESULTS: To address the above...

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Identifiers

PMID: 24467687
DOI: 10.1186/1471-2105-15-28
PMCID: PMC3916084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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