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Improved FFPE Tissue Cancer-Associated Protein Detection using a Recombinant Protein Spectral Library (rPSL) DIA-MS Workflow

2026-04-14

Abstract excerpt

<title>Abstract</title> <p>Formalin-fixed, paraffin-embedded (FFPE) tumour archives represent a vast, clinically annotated resource for biomarker discovery. However, reliable detection and quantification of lower-abundance proteins, particularly cancer biomarkers, remain challenging. Here, we applied an optimised recombinant protein spectral library data-independent acquisition MS (rPSL-DIA-MS) workflow to FFPE c...

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Literature Corpus work
f355cd40-ad90-5a19-b11f-14e6bab27482
DOI
10.21203/rs.3.rs-9258373/v1
Open publication

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