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MetaPilot: genome-aware adaptive search-space refinement for unified DDA and DIA metaproteomics

2026-08-27

Abstract excerpt

<title>Abstract</title> <p>Metaproteomics directly measures microbial protein expression in complex communities, but analysis is constrained by large, poorly structured search spaces. Microbial gene catalogues provide broad coverage, but their pooled organization hinders genome-level evidence accumulation and consistent DDA and DIA analysis. Here, we present MetaPilot, a genome-aware workflow that uses conserved...

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Literature Corpus work: f91795b8-8a81-50cd-a5b5-cc8fba8b273b
DOI: 10.21203/rs.3.rs-10087713/v1

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