Article

On the limits of 16S rRNA gene-based metagenome prediction and functional profiling

2023-11-08

Abstract excerpt

Molecular profiling techniques such as metagenomics, metatranscriptomics or metabolomics offer important insights into the functional diversity of the microbiome. In contrast, 16S rRNA gene sequencing, a widespread and cost-effective technique to measure microbial diversity, only allows for indirect estimation of microbial function. To mitigate this, tools such as PICRUSt2, Tax4Fun2, PanFP and MetGEM infer functio...

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Literature Corpus work: f345201c-5c13-58e0-81a9-1cce3617612b
DOI: 10.1101/2023.11.07.564315

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