Article
Proteobacteria explain significant functional variability in the human gut microbiome.
Microbiome - 23 Mar 2017
Bradley Patrick H, Pollard Katherine S
Abstract excerpt
BACKGROUND: While human gut microbiomes vary significantly in taxonomic composition, biological pathway abundance is surprisingly invariable across hosts. We hypothesized that healthy microbiomes appear functionally redundant due to factors that obscure differences in gene abundance between individuals. RESULTS: To account for these biases, we developed a powerful test of gene variability called CCoDA, which is...
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