Article

Enhancing inference of differential gene expression in metatranscriptomes from human microbial communities

2025-09-16

Abstract excerpt

<h4>ABSTRACT</h4> Metatranscriptomic (MTX) sequencing quantifies gene expression from the collective genomes of microbial communities (microbiomes), enabling assessment of functional activity rather than functional potential. While differential expression testing is essential for RNA-sequencing analysis, current metatranscriptomic approaches have only been benchmarked on simulated data, resulting in a lack of sta...

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Literature Corpus work: bd314514-5442-50f4-b298-7f6812520b87
DOI: 10.1101/2025.09.11.675436

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